PPIA antibody
Product Specifications
Background
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Synonyms
Peptidyl-prolyl cis-trans isomerase A (PPIase A)|Cyclophilin A|Cyclosporin A-binding protein|Rotamase A|Peptidyl-prolyl cis-trans isomerase A, N-terminally processed|PPIA|CYPA
UniProt
P62937
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
peptidylprolyl isomerase A(cyclophilin A)
Target
PPIA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:3000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
18 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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