CXCR2 antibody
Product Specifications
Background
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Synonyms
C-X-C chemokine receptor type 2 (CXC-R2, CXCR-2)|CDw128b|GRO/MGSA receptor|High affinity interleukin-8 receptor B (IL-8R B)|IL-8 receptor type 2|CXCR2|IL8RB
Gene ID
3579
UniProt
P25025
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
interleukin 8 receptor, beta
Target
CXCR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Immunology, Cardiovascular, Cell Division and Proliferation, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP:1:200-1:1000; IHC: 1:50-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45-50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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