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CUEDC2 antibody

Product Specifications

Background

Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

Synonyms

CUE domain-containing protein 2|CUEDC2|C10orf66

Gene ID

79004

UniProt

Q9H467

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

CUE domain containing 2

Target

CUEDC2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

32 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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