CSPG4 antibody
Product Specifications
Background
CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2 (VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
Synonyms
Chondroitin sulfate proteoglycan 4|Chondroitin sulfate proteoglycan NG2|Melanoma chondroitin sulfate proteoglycan|Melanoma-associated chondroitin sulfate proteoglycan|CSPG4|MCSP
Gene ID
1464
UniProt
Q6UVK1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chondroitin sulfate proteoglycan 4
Target
CSPG4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Cardiovascular, Developmental biology, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
240-250 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Curated Selection
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