CRHR1 antibody
Product Specifications
Background
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.
Synonyms
Corticotropin-releasing factor receptor 1 (CRF-R-1, CRF-R1, CRFR-1) |Corticotropin-releasing hormone receptor 1 (CRH-R-1, CRH-R1) |CRHR1|CRFR|CRFR1|CRHR
Gene ID
1394
UniProt
P34998
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Corticotropin releasing hormone receptor 1
Target
CRHR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Frequently Asked Questions
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