CPSF6 antibody
Product Specifications
Background
Component of the cleavage factor Im complex(CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Synonyms
Cleavage and polyadenylation specificity factor subunit 6|Cleavage and polyadenylation specificity factor 68 kDa subunit (CPSF 68 kDa subunit)|Cleavage factor Im complex 68 kDa subunit (CFIm68)|Pre-mRNA cleavage factor Im 68 kDa subunit|Protein HPBRII-4/7|CPSF6|CFIM68
Gene ID
11052
UniProt
Q16630
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
cleavage and polyadenylation specific factor 6, 68kDa
Target
CPSF6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-68 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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