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CPLX1 antibody

Product Specifications

Background

Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414) . Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414) . Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

Synonyms

Complexin-1|Complexin I (CPX I) |Synaphin-2|CPLX1

Gene ID

10815

UniProt

O14810

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Complexin 1

Target

CPLX1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

15-20 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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