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COL6A1 antibody

Product Specifications

Background

Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts (PMID: 6723253) . It is a heterotrimer composed of three different chains: alpha-1 (VI), alpha-2 (VI), and alpha-3 (VI) or alpha-5 (VI) or alpha-6 (VI) . The alpha-1 (VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.

Synonyms

Collagen alpha-1 (VI) chain|COL6A1

Gene ID

1291

UniProt

P12109

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Collagen, type VI, alpha 1

Target

COL6A1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

140 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

Immunogen Sequence

750-1028aa

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