COL6A1 antibody
Product Specifications
Background
Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts (PMID: 6723253) . It is a heterotrimer composed of three different chains: alpha-1 (VI), alpha-2 (VI), and alpha-3 (VI) or alpha-5 (VI) or alpha-6 (VI) . The alpha-1 (VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.
Synonyms
Collagen alpha-1 (VI) chain|COL6A1
Gene ID
1291
UniProt
P12109
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Collagen, type VI, alpha 1
Target
COL6A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
750-1028aa
Curated Selection
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