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CLCA2 antibody

Product Specifications

Background

Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.

Synonyms

Calcium-activated chloride channel regulator 2|Calcium-activated chloride channel family member 2 (hCLCA2) |Calcium-activated chloride channel protein 3 (CaCC-3, hCaCC-3) |Calcium-activated chloride channel regulator 2, 109 kDa form|Calcium-activated chloride channel regulator 2, 35 kDa form|CLCA2|CACC3

Gene ID

9635

UniProt

Q9UQC9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Chloride channel accessory 2

Target

CLCA2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

141 kDa, 35-40 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

645-901aa

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