CLCA2 antibody
Product Specifications
Background
Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.
Synonyms
Calcium-activated chloride channel regulator 2|Calcium-activated chloride channel family member 2 (hCLCA2) |Calcium-activated chloride channel protein 3 (CaCC-3, hCaCC-3) |Calcium-activated chloride channel regulator 2, 109 kDa form|Calcium-activated chloride channel regulator 2, 35 kDa form|CLCA2|CACC3
Gene ID
9635
UniProt
Q9UQC9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Chloride channel accessory 2
Target
CLCA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
141 kDa, 35-40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
645-901aa
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