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CLDN4-specific antibody

Product Specifications

Background

Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small(20-27 kDa) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. This antibody is specifically against claudin 4.

Synonyms

Claudin-4|Clostridium perfringens enterotoxin receptor (CPE-R, CPE-receptor)|Williams-Beuren syndrome chromosomal region 8 protein|CLDN4|CPER|CPETR1|WBSCR8

UniProt

O14493

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

claudin 4

Target

CLDN4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

22 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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