CIT antibody
Product Specifications
Background
Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Synonyms
Citron Rho-interacting kinase (CRIK)|Serine/threonine-protein kinase 21|CIT|CRIK|KIAA0949|STK21
Gene ID
11113
UniProt
O14578
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
citron(rho-interacting, serine/threonine kinase 21)
Target
CIT
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cell Division and Proliferation, Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
230 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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