BIRC2 antibody
Product Specifications
Background
BIRC2 (also known as cIAP1) is a member of the inhibitor of apoptosis protein (IAP) family. The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway (PMID: 15265700) . This cIAP1 antibody can bind both full length (70kd) and cleaved form (60kd) of the protein.
Synonyms
Baculoviral IAP repeat-containing protein 2|Cellular inhibitor of apoptosis 1 (C-IAP1) |IAP homolog B|Inhibitor of apoptosis protein 2 (hIAP-2, hIAP2) |RING finger protein 48|RING-type E3 ubiquitin transferase BIRC2|TNFR2-TRAF-signaling complex protein 2|BIRC2|API1|MIHB|RNF48
UniProt
Q13490
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Baculoviral IAP repeat-containing 2
Target
BIRC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa, 60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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