BIRC2 antibody
Product Specifications
Background
BIRC2(also known as cIAP1) is a member of the inhibitor of apoptosis protein(IAP) family. The inhibitor of apoptosis(IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway(PMID: 15265700). This cIAP1 antibody can bind both full length(70kd) and cleaved form(60kd) of the protein.
Synonyms
Baculoviral IAP repeat-containing protein 2|Cellular inhibitor of apoptosis 1 (C-IAP1)|IAP homolog B|Inhibitor of apoptosis protein 2 (hIAP-2, hIAP2)|RING finger protein 48|RING-type E3 ubiquitin transferase BIRC2|TNFR2-TRAF-signaling complex protein 2|BIRC2|API1|MIHB|RNF48
UniProt
Q13490
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
baculoviral IAP repeat-containing 2
Target
BIRC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa, 60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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