CHST15 antibody
Product Specifications
Background
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4) ) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4) -GlcA (2SO4) -GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
Synonyms
Carbohydrate sulfotransferase 15|B-cell RAG-associated gene protein (hBRAG) |N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST) |CHST15|BRAG|GALNAC4S6ST|KIAA0598
Gene ID
51363
UniProt
Q7LFX5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Target
CHST15
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cardiovascular, Metabolism, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa, 69 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Curated Selection
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