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CHST15 antibody

Product Specifications

Background

Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4) ) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4) -GlcA (2SO4) -GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Synonyms

Carbohydrate sulfotransferase 15|B-cell RAG-associated gene protein (hBRAG) |N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST) |CHST15|BRAG|GALNAC4S6ST|KIAA0598

Gene ID

51363

UniProt

Q7LFX5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Target

CHST15

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Cardiovascular, Metabolism, Developmental biology, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

49 kDa, 69 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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