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CENPN antibody

Product Specifications

Background

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.

Synonyms

Centromere protein N (CENP-N) |Interphase centromere complex protein 32|CENPN|C16orf60|ICEN32

Gene ID

55839

UniProt

Q96H22

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Centromere protein N

Target

CENPN

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Epigenetics

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

40 kDa, 25-30 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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