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LCTL rabbit pAb

This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Product Specifications

Background

This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Synonyms

Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)

Gene ID

197021

UniProt

Q6UWM7

Cellular Locus

Endoplasmic reticulum membrane ; Single-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human LCTL AA range: 450-500

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000

Molecular Weight

60kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES15174-1.pdf

Observed Molecular Weight

60 kD

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein .

Other Product Names

Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)

Gene ID (Human)

197021

SwissProt (Human)

Q6UWM7

Available Sizes

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