TFRC antibody
Product Specifications
Background
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
Synonyms
Transferrin receptor protein 1 (TR, TfR, TfR1, Trfr) |T9|p90|Transferrin receptor protein 1, serum form (sTfR) |TFRC|CD71
Gene ID
7037
UniProt
P02786
Host
Mouse
Reactivity
Human
Immunogen
Transferrin receptor protein 1
Target
TFRC
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IHC, WB, IF, FC, IP
Field of Research
Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
4F3
Tested Applications
ELISA, IHC, WB, IF, FC, IP
Immunogen Sequence
511-751aa
Curated Selection
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