CD63 antibody
Product Specifications
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Synonyms
CD63 antigen|Granulophysin|Lysosomal-associated membrane protein 3 (LAMP-3) |Lysosome integral membrane protein 1 (Limp1) |Melanoma-associated antigen ME491|OMA81H|Ocular melanoma-associated antigen|Tetraspanin-30 (Tspan-30) |CD63|MLA1|TSPAN30
Gene ID
967
UniProt
P08962
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
CD63 molecule
Target
CD63
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Cancer, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
Immunogen Sequence
104-209aa
Curated Selection
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