CD44 antibody
Product Specifications
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Synonyms
CD44 antigen|CDw44|Epican|Extracellular matrix receptor III (ECMR-III) |GP90 lymphocyte homing/adhesion receptor|HUTCH-I|Heparan sulfate proteoglycan|Hermes antigen|Hyaluronate receptor|Phagocytic glycoprotein 1 (PGP-1) |Phagocytic glycoprotein I (PGP-I) |CD44|LHR|MDU2|MDU3|MIC4
Gene ID
960
UniProt
P16070
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
CD44 molecule (Indian blood group)
Target
CD44
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Stem Cells, Immunology, Cardiovascular, Cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
79 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
20-178aa
Curated Selection
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