ITGAX antibody
Product Specifications
Background
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a type I transmembrane protein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.
Synonyms
Integrin alpha-X|CD11 antigen-like family member C|Leu M5|Leukocyte adhesion glycoprotein p150,95 alpha chain|Leukocyte adhesion receptor p150,95|ITGAX|CD11C
Gene ID
3687
UniProt
P20702
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Integrin, alpha X (complement component 3 receptor 4 subunit)
Target
ITGAX
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Cancer, Immunology
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:100-1:400
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
150 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5D4
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
20-352aa
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