CCR5 antibody
Product Specifications
Background
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1/HIV-1.
Synonyms
C-C chemokine receptor type 5 (C-C CKR-5, CC-CKR-5, CCR-5, CCR5) |CHEMR13|HIV-1 fusion coreceptor|CCR5|CMKBR5
Gene ID
1234
UniProt
P51681
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chemokine (C-C motif) receptor 5
Target
CCR5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, FC
Field of Research
Neuroscience, Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, FC
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