CCL17 antibody
Product Specifications
Background
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
CAS Number
9007-83-4
Synonyms
C-C motif chemokine 17|CC chemokine TARC|Small-inducible cytokine A17|Thymus and activation-regulated chemokine|CCL17|SCYA17|TARC
Gene ID
6361
UniProt
Q92583
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
chemokine (C-C motif) ligand 17
Target
CCL17
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Immunology, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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