CBY1 antibody
Product Specifications
Background
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Synonyms
Protein chibby homolog 1|ARPP-binding protein|Cytosolic leucine-rich protein|PIGEA-14|PKD2 interactor, Golgi and endoplasmic reticulum-associated 1|CBY1|ARB1|C22orf2|CBY|PGEA1
Gene ID
25776
UniProt
Q9Y3M2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chibby homolog 1 (Drosophila)
Target
CBY1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30-35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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