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CBX2 antibody

Product Specifications

Background

Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

Synonyms

Chromobox protein homolog 2|CBX2

Gene ID

84733

UniProt

Q14781

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

chromobox homolog 2(Pc class homolog, Drosophila)

Target

CBX2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Stem Cells, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

56-60 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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