CBX2 antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Synonyms
Chromobox protein homolog 2|CBX2
Gene ID
84733
UniProt
Q14781
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chromobox homolog 2 (Pc class homolog, Drosophila)
Target
CBX2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Curated Selection
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