BTG2 antibody
Product Specifications
Background
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity) . Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
Synonyms
Protein BTG2|BTG family member 2|NGF-inducible anti-proliferative protein PC3|BTG2|PC3
Gene ID
7832
UniProt
P78543
Host
Rabbit
Reactivity
Human
Immunogen
BTG family, member 2
Target
BTG2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Cancer, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
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