BHLHA15 antibody
Product Specifications
Background
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity) .
Synonyms
Class A basic helix-loop-helix protein 15 (bHLHa15) |Class B basic helix-loop-helix protein 8 (bHLHb8) |Muscle, intestine and stomach expression 1 (MIST-1) |BHLHA15|BHLHB8|MIST1
Gene ID
168620
UniProt
Q7RTS1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Basic helix-loop-helix family, member a15
Target
BHLHA15
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Neuroscience, Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP
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