B3GNT5 antibody
Product Specifications
Background
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide(LacCer) and neolactotetraosylceramide(nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide(nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
Synonyms
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase|Lactotriaosylceramide synthase (Lc(3)Cer synthase, Lc3 synthase)|UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 (BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5)|B3GNT5
Gene ID
84002
UniProt
Q9BYG0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Target
B3GNT5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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