AZI2 antibody
Product Specifications
Background
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
Synonyms
5-azacytidine-induced protein 2|NF-kappa-B-activating kinase-associated protein 1 (Nak-associated protein 1, Nap1)|TILP|AZI2|NAP1|TBKBP2
Gene ID
64343
UniProt
Q9H6S1
Host
Rabbit
Reactivity
Human
Immunogen
5-azacytidine induced 2
Target
AZI2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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