ATP11B antibody
Product Specifications
Background
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules(Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane.
Synonyms
Phospholipid-transporting ATPase IF|ATPase IR|ATPase class VI type 11B|P4-ATPase flippase complex alpha subunit ATP11B|ATP11B|ATPIF|ATPIR|KIAA0956
Gene ID
23200
UniProt
Q9Y2G3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ATPase, class VI, type 11B
Target
ATP11B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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