ASZ1 antibody
Product Specifications
Background
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity) .
Synonyms
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1|Ankyrin-like protein 1|Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein|ASZ1|ALP1|ANKL1|C7orf7|GASZ
Gene ID
136991
UniProt
Q8WWH4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ankyrin repeat, SAM and basic leucine zipper domain containing 1
Target
ASZ1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48-50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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