GET3 antibody
Product Specifications
Background
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER) . It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
Synonyms
ATPase GET3|Arsenical pump-driving ATPase|Arsenite-stimulated ATPase|Guided entry of tail-anchored proteins factor 3, ATPase|Transmembrane domain recognition complex 40 kDa ATPase subunit|hARSA-I|hASNA-I|GET3|ARSA|ASNA1|TRC40
Gene ID
439
UniProt
O43681
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Target
GET3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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