MAP3K5 antibody
Product Specifications
Background
ASK1 (Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.
Synonyms
Mitogen-activated protein kinase kinase kinase 5|Apoptosis signal-regulating kinase 1 (ASK-1) |MAPK/ERK kinase kinase 5 (MEK kinase 5, MEKK 5) |MAP3K5|ASK1|MAPKKK5|MEKK5
Gene ID
4217
UniProt
Q99683
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mitogen-activated protein kinase kinase kinase 5
Target
MAP3K5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:100-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
155 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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