APPL1 antibody
Product Specifications
Background
Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
Synonyms
DCC-interacting protein 13-alpha (Dip13-alpha) |Adapter protein containing PH domain, PTB domain and leucine zipper motif 1|APPL1|APPL|DIP13A|KIAA1428
Gene ID
26060
UniProt
Q9UKG1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Target
APPL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:2000 - 1:5000; IHC: 1:20 - 1:200; IP: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
1-177aa
Curated Selection
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