ANGPT2 antibody
Product Specifications
Background
ANGPTL2 (angiopoietin-like 2), a member of the Angptl protein family, is predominantly secreted from adipose tissue and the heart. ANGPTL2 consists of an N-terminus with a conserved coiled-coil domain, two glycosylation sites and a C-terminus with a conserved fibrinogen-like domain. It is a key adipocyte-derived inflammatory mediator that links obesity to systemic insulin resistance. ANGPTL2 may play an important role in the pathogenesis of diabetic glomerulopathy.
Synonyms
Angiopoietin-2 (ANG-2) |ANGPT2
UniProt
O15123
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Angiopoietin 2
Target
ANGPT2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology, Cardiovascular, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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