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ANGPT2 antibody

Product Specifications

Background

ANGPTL2 (angiopoietin-like 2), a member of the Angptl protein family, is predominantly secreted from adipose tissue and the heart. ANGPTL2 consists of an N-terminus with a conserved coiled-coil domain, two glycosylation sites and a C-terminus with a conserved fibrinogen-like domain. It is a key adipocyte-derived inflammatory mediator that links obesity to systemic insulin resistance. ANGPTL2 may play an important role in the pathogenesis of diabetic glomerulopathy.

Synonyms

Angiopoietin-2 (ANG-2) |ANGPT2

UniProt

O15123

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Angiopoietin 2

Target

ANGPT2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Immunology, Cardiovascular, Developmental biology, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

57 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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