IAPP antibody
Product Specifications
Background
IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Synonyms
Islet amyloid polypeptide|Amylin|Diabetes-associated peptide (DAP) |Insulinoma amyloid peptide|IAPP
Gene ID
3375
UniProt
P10997
Host
Rabbit
Reactivity
Human
Immunogen
Islet amyloid polypeptide
Target
IAPP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
10 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
Immunogen Sequence
34-70aa
Curated Selection
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