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PRKAA1 antibody

Product Specifications

Background

The mammalian 5-prime-AMP-activated protein kinase(AMPK) appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. PRKAA1 is also named as AMPK1, ACACA kinase, HMGCR kinase. It is a mammalian homologue of sucrose non-fermenting protein kinase(SNF-1), which belongs to a serine/threonine protein kinase family. It has 2 isoforms produced by alternative splicing.

Synonyms

5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1)|Acetyl-CoA carboxylase kinase (ACACA kinase)|Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase)|Tau-protein kinase PRKAA1|PRKAA1|AMPK1

Gene ID

5562

UniProt

Q13131

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

protein kinase, AMP-activated, alpha 1 catalytic subunit

Target

PRKAA1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Cardiovascular, Metabolism, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

63 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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