PRKAA1 antibody
Product Specifications
Background
The mammalian 5-prime-AMP-activated protein kinase (AMPK) appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. PRKAA1 is also named as AMPK1, ACACA kinase, HMGCR kinase. It is a mammalian homologue of sucrose non-fermenting protein kinase (SNF-1), which belongs to a serine/threonine protein kinase family. It has 2 isoforms produced by alternative splicing.
Synonyms
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) |Acetyl-CoA carboxylase kinase (ACACA kinase) |Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase) |Tau-protein kinase PRKAA1|PRKAA1|AMPK1
Gene ID
5562
UniProt
Q13131
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein kinase, AMP-activated, alpha 1 catalytic subunit
Target
PRKAA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
63 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
377-449aa
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