AP2A1 antibody
Product Specifications
Background
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma) . The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
Synonyms
AP-2 complex subunit alpha-1|100 kDa coated vesicle protein A|Adaptor protein complex AP-2 subunit alpha-1|Adaptor-related protein complex 2 subunit alpha-1|Alpha-adaptin A|Alpha1-adaptin|Clathrin assembly protein complex 2 alpha-A large chain|Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit|AP2A1|ADTAA|CLAPA1
Gene ID
160
UniProt
O95782
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Adaptor-related protein complex 2, alpha 1 subunit
Target
AP2A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Developmental biology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
108 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Curated Selection
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