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SERPINA3 antibody

Product Specifications

Background

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Synonyms

Alpha-1-antichymotrypsin (ACT) |Cell growth-inhibiting gene 24/25 protein|Serpin A3|Alpha-1-antichymotrypsin His-Pro-less|SERPINA3|AACT

Gene ID

12

UniProt

P01011

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

Target

SERPINA3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB, IF

Field of Research

Cancer, Immunology, Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, WB, IF

Immunogen Sequence

104-326aa

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