ALKBH4 antibody
Product Specifications
Background
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
Synonyms
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|Alkylated DNA repair protein alkB homolog 4|DNA N6-methyl adenine demethylase ALKBH4|Lysine-specific demethylase ALKBH4|ALKBH4|ABH4
Gene ID
54784
UniProt
Q9NXW9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
AlkB, alkylation repair homolog 4 (E. coli)
Target
ALKBH4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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