ALKBH4 antibody
Product Specifications
Background
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84'(K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
Synonyms
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|Alkylated DNA repair protein alkB homolog 4|DNA N6-methyl adenine demethylase ALKBH4|Lysine-specific demethylase ALKBH4|ALKBH4|ABH4
Gene ID
54784
UniProt
Q9NXW9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
alkB, alkylation repair homolog 4(E. coli)
Target
ALKBH4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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