ALDOC antibody
Product Specifications
Background
Fructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species (PMID:9363598) . It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer (PMID:21548097) .
Synonyms
Fructose-bisphosphate aldolase C|Brain-type aldolase|ALDOC|ALDC
Gene ID
230
UniProt
P09972
Host
Mouse
Reactivity
Human
Immunogen
Aldolase C, fructose-bisphosphate
Target
ALDOC
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
6F3
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-364aa
Curated Selection
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