ALDOC antibody

Product Specifications

Background

Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Synonyms

Fructose-bisphosphate aldolase C|Brain-type aldolase|ALDOC|ALDC

Gene ID

230

UniProt

P09972

Host

Mouse

Reactivity

Human

Immunogen

aldolase C, fructose-bisphosphate

Target

ALDOC

Clonality

Monoclonal

Isotype

IgG1

Clone

6F3

Applications

ELISA, WB, IHC, IF

Field of Research

Metabolism

Purification

Protein A+G purification

Dilution

WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

39 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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