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AGFG1 antibody

Product Specifications

Background

Required for vesicle docking or fusion during acrosome biogenesis (By similarity) . May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Synonyms

Arf-GAP domain and FG repeat-containing protein 1|HIV-1 Rev-binding protein|Nucleoporin-like protein RIP|Rev-interacting protein|Rev/Rex activation domain-binding protein|AGFG1|HRB|RAB|RIP

Gene ID

3267

UniProt

P52594

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ArfGAP with FG repeats 1

Target

AGFG1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Immunology, Signal Transduction, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

58 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

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