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AGBL3 antibody

Product Specifications

Background

Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. Isoform 2: Metallocarboxypeptidase that mediates tubulin deglutamylation.

Synonyms

Cytosolic carboxypeptidase 3|ATP/GTP-binding protein-like 3|Protein deglutamylase CCP3|AGBL3|CCP3

Gene ID

340351

UniProt

Q8NEM8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ATP/GTP binding protein-like 3

Target

AGBL3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

73 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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