ADIPOQ antibody

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Adiponectin|30 kDa adipocyte complement-related protein|Adipocyte complement-related 30 kDa protein (ACRP30) |Adipocyte, C1q and collagen domain-containing protein|Adipose most abundant gene transcript 1 protein (apM-1) |Gelatin-binding protein|ADIPOQ|ACDC|ACRP30|APM1|GBP28