ACVR1C antibody

Product Specifications

Background

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]) .

Synonyms

Activin receptor type-1C|Activin receptor type IC (ACTR-IC) |Activin receptor-like kinase 7 (ALK-7) |ACVR1C|ALK7

Gene ID

130399

UniProt

Q8NER5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Activin A receptor, type IC

Target

ACVR1C

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Stem Cells, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

60 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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