ACTA2 antibody
Product Specifications
Background
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms
Actin, aortic smooth muscle|Alpha-actin-2|Cell growth-inhibiting gene 46 protein|Actin, aortic smooth muscle, intermediate form|ACTA2|ACTSA|ACTVS|alpha-Smooth Muscle Actin|α-SMA
Gene ID
59
UniProt
P62736
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Actin, alpha 2, smooth muscle, aorta
Target
ACTA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
Curated Selection
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