YWHAQ antibody
Product Specifications
Background
14-3-3 theta(also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms(gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo-and hetero-dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Synonyms
14-3-3 protein theta|14-3-3 protein T-cell|14-3-3 protein tau|Protein HS1|YWHAQ
Gene ID
10971
UniProt
P27348
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Target
YWHAQ
Clonality
Monoclonal
Isotype
IgG1
Clone
8D2
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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