YWHAQ antibody
Product Specifications
Background
14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo-and hetero-dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Synonyms
14-3-3 protein theta|14-3-3 protein T-cell|14-3-3 protein tau|Protein HS1|YWHAQ
Gene ID
10971
UniProt
P27348
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Target
YWHAQ
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, IP, IHC, WB
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, IP, IHC, WB
Immunogen Sequence
A synthetic peptide
Curated Selection
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