Fmoc-PEA
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) [1].
Product Specifications
CAS Number
[329223-23-6]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-pea.html
Purity
99.47
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOP(O)(O)=O
Molecular Formula
C17H18NO6P
Molecular Weight
363.30
Precautions
H302, H315, H319, H335
References & Citations
[1]GARBACCIO, Robert, M., et al. PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES. WO2015153401A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Phosphatase Cleavable Linker
Available Sizes
Curated Selection
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